Exercise is a vitally important lifestyle choice for all aspects of health throughout our lifespan. Exercise is key in harnessing hormones to drive positive adaptive changes for optimising health and athletic performance. Reviewing and modifying the type of exercise with increasing age and the training load of master athletes is important to match changes in hormones. This includes the marked hormone shifts that every menopausal woman will experience. Exercise matters for enjoying healthy ageing and the transition through menopause and beyond.